A body has been found at a property in Port Erin, following a fire during the night.
Fire crews and police officers attended a blaze in Rowany Drive at about 2.15am.
The death is currently being treated as unexplained and enquiries are continuing.
The coroner of inquests has been informed.
Anyone who was in the area at the time is asked to contact police on 631212 or the anonymous Crimestoppers number, 0800 555 111.