The Mountain Road will close at 9.30 on Saturday as the first day of racing gets underway at TT 2013.
The rest of the course will close at 10am, with a practice session for the Superbike, Supersport and Superstock machines at 10.30am.
The Sure Sidecar Race 1 will begin at 12.30pm, with a Lightweight and Supersport practice at 2.20pm
There will then be a two-lap practice for the Superbikes and Superstocks at 3.40pm, followed by a 40-minute TT Zero practice with roads opening at 5pm.
Meanwhile, the Dainese Superbike race will go ahead on Mad Sunday, with the Mountain Road closing at 1pm and the rest of the course for 1.30, in order to give the race a 2.15 start.
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