Rugby - Douglas and Ramsey meet for the third time this season.
The previous meeting in South Lancashire and Cheshire Division Two at Mooragh Park ended in a draw but Douglas won a tight Manx Cup semi-final.
Vagabonds are away to Ellesmere Port.
And Vagabonds Ladies, without a win all season, travel to Sheffield.
The Manx Trophy clash between Southern Nomads and Douglas "B" is off as Douglas are unable to field a team.