In Football, Premier League leaders Laxey have the week off so it gives their rivals a chance to catch up.
Second placed St. Mary's can close to within a point if they see off the challenge of fourth in the table Peel at The Bowl.
Champions St. George's face Corinthians.
In Rugby, Douglas, Ramsey and Vagabonds are all in South Lancashire and Cheshire Division Two.
And the Hockey Mixed Premier League opens with Champions Valkyrs "A" facing Vikings "A" at the National Sports Centre at 2.05pm.
Ravens back at The Bowl to face AFC Liverpool
FC Isle of Man hoping to break duck against Merseyside visitors
Rugby: Douglas face Ramsey in last Manx Cup qualifier
Both sides could meet again in final next week
Manx athletes to descend on 2024 London Marathon
The iconic event sees people from all walks of life take on mammoth challenge
Football: Peel and Onchan to meet in Women's FA Cup Final
Hospital Cup & Junior Cup campaigns begin this weekend (Fixtures: 20-21 Apr)
Higgins earns FC Isle of Man draw at Irlam
Ravens claim result in final away game of campaign
Payne & Rousseau prepare for world championship opener
Duo already claimed double French championship victory this month
