Douglas went down 18-10 on their trip to Orrell Anvils.
The Manx side trailed 10-7 at half-time after skipper Bryn Snellgrove picked up a try and a conversion to pull them back into the game after they had conceded 10 early points.
A Snellgrove drop goal early in the second half levelled the scores but Orrell stole the game with a try and a penalty in the closing stages.
Ravens on the road at Euxton Villa
FC Isle of Man four unbeaten ahead of meeting with newly-promoted side
Powerlifting: IoM sets new best points haul at Home Nations
Lindsay and Skillicorn also take wins during meeting in Birmingham
Michael Dunlop receives MBE
Royal recognition for most successful TT competitor of all time
Netball: Defeat for Rams against Papua New Guinea
Third straight loss for Manx side at Singlife Nations Cup
