Repeat of final from two seasons ago
Football - with the ECAP FA Cup not being played last season due to the Covid-19 pandemic, Peel are still the current holders of the trophy.
The westerners travel to The Bowl on Saturday afternoon to face the side they beat in the last final St. Mary's.
Peel have featured in the last four finals winning two and losing the others.
St. Mary's will go into the match as favourites as they have picked up 16 more points than their opponents in the Premier League.
There are two other ties featuring top flight sides up against each other.
Ayre host Old Boys and St John's travel to Laxey.
Current Premier League leaders Corinthians are away at Onchan, St. George's host Governor's Athletic, Ramsey welcome Braddan and Douglas Royal take a trip south to Colby.
At least three Division Two sides will make it through to the next round from the games between Castletown and Pulrose, Douglas & District against Gymns and Michael v Foxdale.