Ramsey face big test at Aspull
All three Manx sides in the South Lancashire and Cheshire League are away from home.
Division One leaders Douglas travel to Widnes looking for a ninth straight win and to consolidate their five point advantage at the top.
Vagabonds go to Marple who are a couple of places higher up the Division Two table.
And Ramsey have a huge test in Division Three.
The northerners are second but tackle leaders Aspull who have won all eight games this season and are eleven points ahead of their Manx opponents.