Points a priority to secure place
While title rivals St. George's and Peel look certain of making the Railway Cup semi-finals at the halfway stage of the season, the remaining two places are still up for grabs.
Champions and leaders St. George's play Ayre at Glencrutchery Road while Peel welcome western neighbours St. John's to Douglas Road.
Third placed Rushen are also at home against Ramsey.
Two sides still in with a shout for a Railway Cup berth meet at Blackberry Lane when Old Boys and Laxey clash.
Corinthians meet Ramsey Youth Centre at Ballafletcher and Union Mills travel to The Bowl to play St. Mary's.