Both sides met in the tournament last season
FC Isle of Man has had it's first confirmed competitive fixture announced for the 2022/23 season.
The Ravens will travel to face AFC Liverpool in the first round of the Macron Cup on Saturday, 15 October.
Both sides met in the competition at the Marine Travel Arena last season on Wednesday, 16 March, 2022.
AFC Liverpool ran out 2-0 winners on the night on Merseyside - that result remains FC Isle of Man's only defeat so far in 2022.
Separately, both sides are set to face each other in the league this coming campaign in the NWCFL Premier Division.
Fixtures for the league are still to be confirmed.