Champs host Ramsey
With a big advantage of twelve points at the top of the Canada Life Premier League, St. George's face a Ramsey side fighting to stay up at Glencrutchery Road.
Second placed Peel have four games in hand but can't afford to slip at home to sixth-in-the-table Laxey.
The other sides involved in the battle to avoid the drop all face tough encounters.
Union Mills travel to in-form Corinthians and Marown are at third-placed Rushen.
Old Boys v Ayre and St. Mary's v St. John's were postponed on Friday and pitch inspections at many grounds are expected to take place on Saturday morning.
The last G.H. Corlett Woods Cup quarter-final will be played at Ballafletcher when Douglas Royal host Division Two runaway leaders Douglas Athletic.
Nickolas Ellis impresses at Le Mans
Caomhan Canny hoping for TT return after 2026 withdrawal
Classic sidecars confirmed for 2026 Southern 100
TT launches sustainability review into Sidecar class
