Parkinson Railway Cup holders Peel will face Old Boys at Blackberry Lane as they bid to defend the trophy.
Saturday evening’s draw live on Manx Radio paired the sides together.
The other clash will see Premier League leaders St George’s host Laxey.
St George’s v Laxey
Old Boys v Peel
Ties to be played Saturday, November 27 (kick-off 1.15pm)
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