Parkinson Railway Cup holders Peel will face Old Boys at Blackberry Lane as they bid to defend the trophy.
Saturday evening’s draw live on Manx Radio paired the sides together.
The other clash will see Premier League leaders St George’s host Laxey.
St George’s v Laxey
Old Boys v Peel
Ties to be played Saturday, November 27 (kick-off 1.15pm)
Football: New leader sought to spearhead women's game
FA begins search for new development officer
Island earns 'unique status' for local athletes support scheme
Dual initiative aids youngsters with studies as well as sporting ambitions
Snooker: Defending champions Blinders beaten on opening day
Two new teams also part of gameweek one of 24/25 season
Powerlifting: IoM takes another impressive commonwealth medal haul
21 medals secured between 11 athletes in South Africa
